Postmarketing cases of respiratory despair, like fatalities, have been described with usage of promethazine in pediatric sufferers less than two years of age. An array of bodyweight-primarily based doses of promethazine have resulted in respiratory depression in these clients.
NMS is a serious problem that can cause death. Quit taking promethazine/dextromethorphan and get in touch with your healthcare service provider straight away in the event you have any of the next symptoms.
Serious Allergic Reactions. Promethazine/dextromethorphan may well induce allergic reactions, which may be major. Stop getting promethazine/dextromethorphan and have help instantly for those who have any of the next symptoms of a significant allergic reaction.
Carcinogenesis, Mutagenesis, Impairment of Fertility Long-time period animal studies have not been done to assess the carcinogenic likely of promethazine, nor are there other animal or human facts relating to carcinogenicity, mutagenicity, or impairment of fertility with this drug. Promethazine was nonmutagenic from the Salmonella test method of Ames.
Do not share promethazine/dextromethorphan with other people today, even when they have precisely the same condition as you. It might hurt them.
Because recurrences of NMS have been noted with phenothiazines, the reintroduction of promethazine HCl ought to be cautiously considered.
Pregnancy. It's not at all regarded if or how promethazine/dextromethorphan could impact pregnancy or damage an unborn baby.
This may not be an entire list of medicines that will interact with promethazine/phenylephrine. Usually check with your Health care supplier.
EPINEPHRINE SHOULD NOT BE USED, given that its use in patients with partial adrenergic blockade may perhaps even further decrease the blood pressure. Extrapyramidal reactions could possibly be treated with anticholinergic antiparkinson agents, diphenhydramine, or barbiturates. Oxygen can also be administered.
It might make the skin more sensitive to daylight. Stay clear of exposing your skin to solid sunlight, use a sunscreen lotion or make confident the skin is protected with garments.
Halt taking promethazine/phenylephrine and simply call your Health care supplier in case website you have any of the following signals that a seizure is happening or could happen.
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